Henderson features an attractive array of industrial and commercial locations to meet the needs of expanding and/or relocating businesses. Three industrial zoning designations are currently utilized in Henderson to provide a broad range of opportunities for light manufacturing, research and development, warehouse/distribution, and service uses: IP - Industrial Park District, IL - Limited Industrial District, and IG - General Industrial District. Henderson also features a full range of possible commercial locations for corporate office, call center, retail, and service uses.
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Henderson - Major Business Parks (30+ acres)

| Business Park |
Major Tenants/Projects |
Available Buildings |
| 1) Gibson Business Park | Ocean Spray Cranberries, Inc., Pacific Business Center, Suncrest Commerce Center | Yes |
| 2) Black Mountain Business Park | Graham Packaging Company, ITT Technical Institute, Quality Corrections & Inspections, Black Mountain Corporate Center, Touro University - Nevada | Yes |
| 3) Traverse Point Center | Traverse Point Commerce Center | Yes |
| 4) Green Valley Business Park, Whitney Mesa Business Park | Ethel M Chocolates, Allen Tel Products, University of Southern Nevada | Yes |
| 5) Henderson Executive Airport Center, South 15 Airport Center, Limited Transition Area (LTA) | Levi Strauss & Co., Henderson Quail Air Center, VNE Jet, South 15 Airport Center | Yes |
| 6) Conestoga Industrial Area | Poly West, Interstate Brands Corp. | Yes |
| 7) Cornerstone | Nevada Orthopedic & Spine Center | Yes |
| 8) Eastside and Sunpac Industrial Areas | Armand Manufacturing, Advanced Superabrasives, Inc. | Yes |
| 9) Black Mountain Industrial Center | Pro-Caps Laboratories, EMT West, Henderson Commerce Center, Las Vegas Distillery | Yes |
| 10) Green Valley Corporate Center | Vegas.com, Regis University, American Nevada Company, The Art Institute of Las Vegas | Yes |
| 11) Green Valley Corporate Center South | Amica, International Academy of Design & Technology, DeVry University | Yes |
| 12) Siena Office Park | Western Regional Center for Brain & Spine | Yes |